|
Symbol Name ID |
F2
coagulation factor II MGI:88380 |
| Darker colors indicate more annotations |
| Human Phenotypes | Leukopenia |
Pericarditis |
Lymphadenopathy |
Splenic rupture |
Hepatosplenomegaly |
Helicobacter pylori infection |
Lupus nephritis |
Nephritis |
Abnormality of the immune system |
Discoid lupus rash |
Malar rash |
Serositis |
Decreased circulating complement C3 concentration |
Decreased circulating complement C4 concentration |
Autoimmunity |
Antineutrophil antibody positivity |
Perinuclear antineutrophil antibody positivity |
Antinuclear antibody positivity |
Anti-dsDNA antibody positivity |
Anti-La/SS-B antibody positivity |
Anti-Sm antibody positivity |
Anti-U1 ribonucleoprotein antibody positivity |
Antiphospholipid antibody positivity |
Systemic lupus erythematosus |
| Disease(s) Associated with F2 | ||||||||||||||||||||||||
| factor VIII deficiency | ||||||||||||||||||||||||
| pre-eclampsia | ||||||||||||||||||||||||
| systemic lupus erythematosus |
| Mouse Phenotypes | decreased susceptibility to induced arthritis |
decreased susceptibility to endotoxin shock |
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| Availability | Mouse Genotype | ||
| F2tm2Jld/F2+ | |||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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